|JULY 2013||DR. PIMWIMON JANSANG MD7|
| NEURO–DEGENERARATIVE DISEASES|
Today’s Speaker, Dr. Pimwimon Jansang MD, discussed the phenomenon of our Brain.
The Brain is the commander of our daily life and affects everything we think and do. One should do one’s utmost to keep one’s brain in the best possible condition. Have your exercises, healthy food, good sleep and regular living patterns. Avoid stress andsmoking. Be Happy.
To her question if some persons in the room suffered a Stroke, have (the early symptoms of) Alzheimer or Parkinson, only a few responded.
In advance of the meeting a Quiz was distributed. The score gives you an indication, to your treating of your brain. The results did surprise us.
She continued that, even you live the proper life and follow all advises, you may have some medical problems; due to hereditary, influences our Medicals are not yet aware of or beyond your control.
A stroke occurs in case:
– Of sudden bleeding in the brain, if it damages brain cells
– The flow of oxygen
– rich blood to a portion of the brain is blocked.Without oxygen, brain cells start to die after a few minutes only.
We distinguish 2 main kinds; Ischemic stroke (severe) / Hemorrhagic stroke (mild)
Ischemic Stroke is if artery, which supplies oxygen–rich blood to the brain, becomes blocked.
A TIA (Transient ischemic attack) or mini stroke occurs if blood–flow to a portion of the brain is blocked for a short time only. Damage to the brain cells isn’t permanent.
Hemorrhagic Stroke is, if an artery in the brain leaks blood or ruptures.
Indications you suffered a (mild) stroke are, among others; Irregularities with your Face, arm, speech etc. Be aware that maybe not you but your partner, friends etc see these before you do yourself.
As soon as one has an indication or feeling one has a problem. Do not hesitate and call for immediate assistance Bangkok Hospital Udon 1719 or the General Emergency Number 1619
Indications are: Face, Arm, Speech and Time =FAST=.
The first couple of hours are of utmost importance. As soon as you suffer a stroke or have an indication for a coming stroke, you should have medical treatment at once and certainly within 3 hours.
In case and very quick after the brain cells have a lack of oxygen they die. Medicines shall be administered within 4.5
Recombinant tissue plasminogen activator (rtPA) within 4.5 hours
Antiplatelet medicine or/and high dose of Lipid lowering agent
Minimize Risk Factors
– No smoking
– Have a healthy diet
– Maintain a healthy weight
– Being physically active.
The good news is that you can remain mentally sharp, retain your memory and avoid Parkinson’s and Alzheimer’s disease.
We distinguish 2 main groups; Alzheimer and Parkinson, each having many variations.
Alzheimer and Dementia
Alzheimer’s disease, first described by the German neurologist Alois Alzheimer, is the mostcommon cause of Dementia.
The term ‘Dementia’ describes a set of symptoms which can include loss of memory, mood changes, and problems with communication and reasoning. These symptoms occur when the brain is damaged by certain diseases and conditions, including Alzheimer’s disease.
Alzheimer’s disease is a physical disease affecting the brain. Slowly destroying memory and thinking skills. During the course of the disease, protein ‘plaques’ and ‘tangles’ develop in the structure of the brain, leading to the death of brain cells.
People with Alzheimer also have a shortage of some important chemicals in their brain.
These chemicals are involved with the transmission of messages within the brain.
Alzheimer’s is a progressive disease, which means that gradually, over time, more parts of the brain are damaged. As this happens, the symptoms become more severe .
Currently, there is No Cure.
Mild Cognitive Impairment (MCI)
Recently, the termMCI is being used when a person has difficulty remembering things or thinking clearly but the symptoms are not severe enough to warrant a diagnosis of Alzheimer’s disease
A Quiz with 30 questions has been developed, of which you must have a positive score >26.
Recent research has shown that individuals with MCI have an increased risk of developing Alzheimer’s disease.
However, the conversion rate from MCI to Alzheimer’s is low (about 10-20 per cent each year), and consequently a diagnosis of MCI does not always mean that the person will go on to develop Alzheimer’s.
New diagnostics are (permanent) being studied.
What causes Alzheimer’s disease?
So far, no one single factor has been identified as a cause for Alzheimer’s disease.
It is likely that a combination of factors, including age, genetic inheritance, environmental factors, lifestyle and overall general health, are responsible.
In some people, the disease may develop silently for many years before symptoms appear.
Age is the greatest risk factor for Dementia. Dementia affects one in 14 persons over the age of 65 and one in six persons over the age of 80. However, dementia is not restricted to older people.
Scientists are currently investigating the genetic background to Alzheimer’s.
It is known that there are a few families where there is a very clear inheritance. This is often in families where the disease appears relatively early in life.
If a parent or other relative has Alzheimer’s, your own chances of developing the disease are only a little higher than if there were no cases of Alzheimer’s in the immediate family.
Research has also shown that people who smoke, and those who have high blood pressure, high cholesterol levels or diabetes, are at increased risk of developing Alzheimer’s.
You can help reduce your risk by not smoking, eating a healthy balanced diet and having regular checks for blood pressure and cholesterol.
Maintaining a healthy weight and leading an active lifestyle combining physical, social and mental activity will also help
There is currently no cure for Alzheimer’s disease. However, drug treatments are available that can temporarily alleviate some symptoms or slow down their progression in somepeople.
People with Alzheimer’s have been shown to have a shortage of the chemical acetylcholine in their brains.
The drugs with donepezil hydrochloride, rivastigmine and galantamine, work by maintaining existing supplies of acetylcholine.
Side–effects are usually minor but may include diarrhea, nausea, insomnia, fatigue and loss of appetite.
Memantine works in a different way from the other three and is the only drug that is recommended for people in both the moderate and severe stages of Alzheimer’s disease.
Side–effects may include dizziness, headaches and tiredness, and – rarely – hallucinations or confusion.
These drugs are not a cure, but they may stabilize some of the symptoms of Alzheimer’s disease for a limited period, typically 6 – 12 months or longer.
The term “Parkinsonism” is a generic descriptive term that refers to the whole category of neurological diseases that causes slowness of movement. The category includes the classic form of Parkinson’s disease, first described by the Englishman James Parkinson, many atypical variants, sometimes called “Parkinson’s Plus Syndromes,” and any other brain disease that resembles Parkinson’s, such as hydrocephalus or drug–induced parkinsonism.
In all cases of Parkinsonism, no matter the cause, there is a disturbance in the dopamine systems of the Basal Ganglia – a part of the brain that controls movement. In all cases, this dopamine deficiency leads to the characteristic combination of tremor, slowness, rigidity and postural instability.
Classic (idiopathic) Parkinson’s is the most common and most treatable form of Parkinsonism. For a significant minority, about 15 percent of all persons with Parkinsonism, one of the atypical variants may be present. These conditions are more serious and less treatable than classic PD.
Drug therapies are available to slow down the progression of the disease only.
There are many medications available to treat the symptoms of Parkinson’s, although none yet that actually reverse the effects of the disease.
You may boost your brain–power by consuming the Healthy Foods, have a wide Variety, a good Balance and be Moderate
Good Super Foods are:
– Green tea, Oat–meat, Wild salmon, soy, kale and other brassica vegetables
– Apple, Nuts, Egg, Sweet potato, Cereal
– Broccoli, Goji berry, Blue berry, Quinoa, Garlic, Sea–vegetables, Micro–plants (antioxidants)
– Chives, Curry, Avocado, Dark high quality chocolate.
– Olive oil, Vegetable oil
Sleep is a necessary restorative process that affects all aspects of functioning. Sleep is an active process for the brain. Up to 40% of adults are affected, 1/3 adults are affected intermittently and 10% are chronic
Sleep insomnia, definition “I’M UP”, increases the risk to develop brain diseases.
I = Initiate sleep difficulties
M = Maintaining sleep difficulties
U = Un–refreshing sleep
P = Premature awakening
- Tiredness and lack of energy
- Poor concentration, Irritability and/or Depression, Feeling unwell, Less able to enjoy life
- Increased illness
- Sleep Deprivation, Inadequate opportunity for sleep
- Feel sleepy during the day. Insomniacs typically feel tired, not sleepy
- Fall asleep at inappropriate times; while driving, at work, at an interview, while at events.
- Sleep hygiene is a variety of different practices that are necessary to have normal, quality nighttime sleep and full daytime alertness
- The most important sleep hygiene measure is to maintain a regular sleep and wake pattern seven days a week
- appropriate a mount of time in bed between 6.5 – 9 hours (means = 8.3)
- Avoid napping during the day more than 30 minutes
- Avoid stimulants such as caffeine, nicotine, and alcohol after 2 PM
- Exercise can promote good sleep, before sleep > 4 hours
- Ensure adequate exposure to natural light. maintain a healthy sleep–wake cycle
- Associate your bed with sleep
- Make sure, your sleep environment is pleasant and relaxing, not too hot, too cold or too bright
- Try to avoid emotionally upsetting conversations and activities before trying to go to sleep
Physical and Brain exercise
- Deep breathe exercise
- De–stress through exercise 30 minutes a day
- Lift weights at least once a week
- Express your emotions, either positive or negative, Think positively, Use your imagination
- Maintain social activities
- Cooking, driving, reading, crossword puzzles, card games and projects
- Relax ; meditation, massage, sauna, music
Stam–cells might be a treatment / therapy in the future